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There's always another pathlibfemme ( 08/30/2004, 23:52:11 )In the Proceedings of the Asian Reproductive Biotechnology from Feb 2000, Wakayama published a paper, which the internet translated thus:"Thus far a cloned mouse is by no means a perfect copy of the original mouse as far as placenta, body weight, and methylation status of genome DNA is concerned.However, obesity and enlarged placenta are not heritable and are absent from the progeny of clone x clone and clone x wild type crosses. This implies that nuclear transfer clone-associated obesity and enlarged placenta are caused by imprinting and/or reprogramming phenomenon that is corrected during gametogensis. It is probably that these clone-specific abnormalities were not inherited even after re-cloning, in which a clone was produced from a clone, because we succeed in producing at least six generation clones. The relationship between reiterative cloning generates animals and aging is very interested (sic). However, at the organism level, there is no evidence of age-related attrition of learning ability (as judged by Morris water maze and Krushinsky tests), or of strength, agility, co-ordination or home cage activity compared to non-cloned controls. At a cellular level we determined telomeres length in peripheral blood lymphocytes of clones and found no evidence of shortened telomers in cloned mice. On the contrary, telomeres may exhibit a modest lengthening with each successive generation of clones. Since theses mice were sampled simultaneously, an age related contribution to this increase, in which younger mice have longer telomeres, cannot be excluded. However, these studies on the mouse suggest that cloned animals have telomeres that are at least as long as those of non-cloned counterparts."I'll include the link although I'm not sure it will work. Scan down to page 5. ![]() This Message is being posted for educational purposes, as well as for comment and criticism, by the visitors to the HumanCloning.org Foundation website (www.HumanCloning.org ). Disclaimer: Information provided on this web site is for educatonal purposes only. It is not a substitute for, nor can it replace advice from your own physician. HumanCloning.org™ Established December 11, 2002. |
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