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Illegal Beings: Human Clones
Survival Rate of Clones Increases
libfemme ( 10/08/2003, 11:10:05 )Good news for reproduction cloning today. Scientists have found a way to increase by 8 times the survival rate of cloned mammals. And they may be able to increase it by even more!Scientists at the University of Pennsylvania tried combining two genetically identical cloned mouse embryos. The aggregate embryo was considerably more likely to survive to birth.Researchers took two cells at the four-cell stage and combined them into embryos. When the clone hybrids were transferred back into the uteri of recipient mice the survival rate jumped from 1 percent to 8 percent.Researcher K. John McLaughlin, assistant professor of animal biology said: "The genetic reprogramming of a cloned embryo never seems to occur with 100 percent accuracy.However, the group of genes that fails to reset properly differs in each individual embryo, meaning that each embryo that contributes to an aggregate can help mask the shortcomings of the other. By combining cloned embryos, you might end up with an embryo that's 99 percent reprogrammed rather than just 90 percent."When McLaughlin cut the mouse embryos in half, they found that the expression of key developmental genes was not affected. They believe the developmental deficiencies of some cloned animals have not been due to low cell counts and that a larger blastocyst may communicate in a way that is compromised in a smaller cloned embryo. Penn's School of Veterinary Medicine reports the results in the Oct. 1 issue of the European Molecular Biology Organization Journal
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